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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GDF3 All Species: 23.33
Human Site: S171 Identified Species: 46.67
UniProt: Q9NR23 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NR23 NP_065685.1 364 41387 S171 G K M F V L R S V P W P Q G A
Chimpanzee Pan troglodytes XP_508988 364 41318 S171 G K M F V L R S V P W P Q G A
Rhesus Macaque Macaca mulatta XP_001112644 364 41302 S171 G K M F V L R S V P W P Q G A
Dog Lupus familis XP_534896 365 41219 S171 G K M L V L Q S V P W P R G V
Cat Felis silvestris
Mouse Mus musculus Q07104 366 41509 S172 G R L L F L R S V P G P Q G Q
Rat Rattus norvegicus P49001 393 44364 T191 P V T R L L D T R L V T Q N T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509474 383 41376 Q191 H R Q L L L T Q P L P P G R D
Chicken Gallus gallus Q90751 353 40328 V187 N H G F V V E V V H L D K E N
Frog Xenopus laevis Q9YGV1 354 40298 S164 R K L L V T Q S F R L L H K S
Zebra Danio Brachydanio rerio P35621 355 40183 T167 R K L L Q S Q T L S P G A H A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07713 588 65849 R238 L S L F N M K R P P K I D R S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P48970 395 43818 T205 G T I D I L S T V N S W R S K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 96.4 80.2 N.A. 69.4 29.2 N.A. 43.5 30.2 42.3 42 N.A. 22.1 N.A. N.A. 30.6
Protein Similarity: 100 99.4 98 87.4 N.A. 79.7 47 N.A. 58.7 49.7 59.6 60.7 N.A. 37.9 N.A. N.A. 48.3
P-Site Identity: 100 100 100 73.3 N.A. 60 13.3 N.A. 13.3 20 20 13.3 N.A. 13.3 N.A. N.A. 20
P-Site Similarity: 100 100 100 86.6 N.A. 73.3 26.6 N.A. 26.6 33.3 40 40 N.A. 40 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 34 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 9 0 0 0 0 9 9 0 9 % D
% Glu: 0 0 0 0 0 0 9 0 0 0 0 0 0 9 0 % E
% Phe: 0 0 0 42 9 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 50 0 9 0 0 0 0 0 0 0 9 9 9 42 0 % G
% His: 9 9 0 0 0 0 0 0 0 9 0 0 9 9 0 % H
% Ile: 0 0 9 0 9 0 0 0 0 0 0 9 0 0 0 % I
% Lys: 0 50 0 0 0 0 9 0 0 0 9 0 9 9 9 % K
% Leu: 9 0 34 42 17 67 0 0 9 17 17 9 0 0 0 % L
% Met: 0 0 34 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 9 0 0 0 0 9 0 0 0 9 9 % N
% Pro: 9 0 0 0 0 0 0 0 17 50 17 50 0 0 0 % P
% Gln: 0 0 9 0 9 0 25 9 0 0 0 0 42 0 9 % Q
% Arg: 17 17 0 9 0 0 34 9 9 9 0 0 17 17 0 % R
% Ser: 0 9 0 0 0 9 9 50 0 9 9 0 0 9 17 % S
% Thr: 0 9 9 0 0 9 9 25 0 0 0 9 0 0 9 % T
% Val: 0 9 0 0 50 9 0 9 59 0 9 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 34 9 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _